BDBM81348 β-Lapachone (A3)::Beta lapachone::R115 (Reactive Blue 2)::beta-Lapachone

SMILES: CC1(C)CCC2=C(O1)c1ccccc1C(=O)C2=O

InChI Key: InChIKey=QZPQTZZNNJUOLS-UHFFFAOYSA-N

Data: 5 KI  23 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 81348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Caspase-1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a	7.5	25
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NADPH--cytochrome P450 reductase (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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NAD(P)H dehydrogenase [quinone] 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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NAD(P)H dehydrogenase [quinone] 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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NAD(P)H dehydrogenase [quinone] 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosyl-DNA phosphodiesterase 2 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4E (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Indoleamine 2,3-dioxygenase 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
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Chaperonin GroEL (Escherichia coli)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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60 kDa heat shock protein, mitochondrial (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Co-chaperonin GroES (Escherichia coli)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Co-chaperonin GroES (Escherichia coli)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
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Thiosulfate sulfurtransferase (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein-glutamine gamma-glutamyltransferase 2 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cocaine esterase (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Liver carboxylesterase 1 (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4E (Human)	BDBM81348 (R115 (Reactive Blue 2) | β-Lapachone (A3) | b...) Show SMILES Show InChI	GoogleScholar	UniChem		3.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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