BDBM81352 US10245267, Example 555::US10709712, Example 555::US9694016, 552::US9694016, 555

SMILES: COc1nnc(cc1N1CCOCC1)-c1cc(NC(=O)c2ccnc(c2)C(C)(C)F)ccc1C

InChI Key: InChIKey=REUREILZLZCFOE-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 81352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf [V600E] (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340E,Y341E] (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340E,Y341E] (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM81352 (US9694016, 555 | US9694016, 552 | US10245267, Exam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair