BDBM81497 4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline::CAS_109028-10-6::CGS 12066B::CHEMBL27403::NSC_123945

SMILES: CN1CCN(CC1)c1nc2cc(ccc2n2cccc12)C(F)(F)F

InChI Key: InChIKey=LXFHSCDLMBZYKY-UHFFFAOYSA-N

Data: 27 KI  17 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 44 hits for monomerid = 81497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Bovine)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Pig)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B/3C/3D/3E (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Pig)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Bovine)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		2.08	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		2.69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		2.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		4.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		7.41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		9.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine 1D receptor (Bovine)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		738	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		871	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		3.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		4.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 3A (Mouse)	BDBM81497 (CAS_109028-10-6 | CHEMBL27403 | 4-(4-Methyl-pipera...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair