BDBM8161 4-{6-methylpyrazolo[1,5-a]pyridazin-3-yl}-N-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine::pyrazolo[1,5-b]pyridazine deriv. 52

SMILES Cc1ccc2c(cnn2n1)-c1ccnc(Nc2ccc(cc2)C(F)(F)F)n1

InChI Key InChIKey=LOAIUSJMQXSEBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8161   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8161(4-{6-methylpyrazolo[1,5-a]pyridazin-3-yl}-N-[4-(tr...)
Affinity DataIC50:  50nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8161(4-{6-methylpyrazolo[1,5-a]pyridazin-3-yl}-N-[4-(tr...)
Affinity DataIC50:  199nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed