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BDBM81684 P1 Phenyl Ring, 26

SMILES: COc1ccc(NC(=O)N2CCCC2C(=O)Nc2ccc(cc2F)-c2ccccc2S(N)(=O)=O)cc1

InChI Key: InChIKey=CKSMADBNTANRQG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 81684   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM81684
PNG
(P1 Phenyl Ring, 26)
Show SMILES COc1ccc(NC(=O)N2CCCC2C(=O)Nc2ccc(cc2F)-c2ccccc2S(N)(=O)=O)cc1
Show InChI InChI=1S/C25H25FN4O5S/c1-35-18-11-9-17(10-12-18)28-25(32)30-14-4-6-22(30)24(31)29-21-13-8-16(15-20(21)26)19-5-2-3-7-23(19)36(27,33)34/h2-3,5,7-13,15,22H,4,6,14H2,1H3,(H,28,32)(H,29,31)(H2,27,33,34)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 873n/an/an/an/an/an/a



Pfizer Inc



Assay Description
FXa inhibition were determined by using an inhibition assay.


Chem Biol Drug Des 69: 444-50 (2007)


Article DOI: 10.1111/j.1747-0285.2007.00520.x
BindingDB Entry DOI: 10.7270/Q2PZ5799
More data for this
Ligand-Target Pair