BDBM81975 4-hydroxyquinoline-2-carboxylic acid::CAS_492-27-3::CHEMBL299155::Kynurenate::NSC_5280455

SMILES: c1ccc2c(c1)c(cc(n2)C(=O)O)O

InChI Key: InChIKey=HCZHHEIFKROPDY-UHFFFAOYSA-N

Data: 6 KI  2 IC50  7 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 81975   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (Rat)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
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G-protein coupled receptor 35 (Human)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.52E+5	n/a	n/a	n/a	n/a
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G-protein coupled receptor 35 (Human)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
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G-protein coupled receptor 35 (Human)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.17E+5	n/a	n/a	n/a	n/a
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Aryl hydrocarbon receptor (Human)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
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Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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G protein-coupled receptor GPR35 (Rat)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a
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G-protein coupled receptor 35 (Human)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.92E+4	n/a	n/a	n/a	n/a
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G-protein coupled receptor 35 (Human)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.52E+5	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1 (Rat)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1 (Rat)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1 (Rat)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 1 (Rat)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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G-protein coupled receptor 35 (Human)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		1.37E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Vesicular glutamate transporter 3 (Rat)	BDBM81975 (4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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