BDBM82053 8-(2-Furyl)theophylline::US9138393, Theophylline::US9144538, Theophylline

SMILES: Cn1c2[nH]cnc2c(=O)n(C)c1=O

InChI Key: InChIKey=ZFXYFBGIUFBOJW-UHFFFAOYSA-N

Data: 19 KI  15 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 82053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 2 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphodiesterase (Bovine)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.72E+6	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.56E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alkaline phosphatase, tissue-nonspecific isozyme (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium channel subfamily K member 2 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.86E+5	n/a	n/a	7.3	22
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Cytochrome P450 3A4 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A1 (Rat)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A1 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		6.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A1 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		6.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A1 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		6.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2b (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2b (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		9.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2b (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		9.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A1 (Rat)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rat)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Rat)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Rat)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A3 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A3 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A3 (Human)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		8.64E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A3 (Rat)	BDBM82053 (8-(2-Furyl)theophylline | US9138393, Theophylline ...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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