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BDBM82158 7-substituted pyrazoloquinolone, 17

SMILES: COc1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O

InChI Key: InChIKey=HIRZXOUNFOFCKD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 82158   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphopantetheine adenylyltransferase (PPAT)


(Enterococcus faecalis (Streptococcus faecalis))
BDBM82158
PNG
(7-substituted pyrazoloquinolone, 17)
Show SMILES COc1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O
Show InChI InChI=1S/C12H9N3O4/c1-19-6-2-3-8-7(4-6)11(16)15-10(13-8)5-9(14-15)12(17)18/h2-5,14H,1H3,(H,17,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.67E+5n/an/an/an/an/an/a



Pfizer, Inc.



Assay Description
PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...


Chem Biol Drug Des 75: 444-54 (2010)


Article DOI: 10.1111/j.1747-0285.2010.00957.x
BindingDB Entry DOI: 10.7270/Q2765CT2
More data for this
Ligand-Target Pair
Phosphopantetheine adenylyltransferase (PPAT)


(Escherichia coli)
BDBM82158
PNG
(7-substituted pyrazoloquinolone, 17)
Show SMILES COc1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O
Show InChI InChI=1S/C12H9N3O4/c1-19-6-2-3-8-7(4-6)11(16)15-10(13-8)5-9(14-15)12(17)18/h2-5,14H,1H3,(H,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.50E+5n/an/an/an/an/an/a



Pfizer, Inc.



Assay Description
PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...


Chem Biol Drug Des 75: 444-54 (2010)


Article DOI: 10.1111/j.1747-0285.2010.00957.x
BindingDB Entry DOI: 10.7270/Q2765CT2
More data for this
Ligand-Target Pair