BDBM82437 CAS_23047-25-8::Lofepramine::NSC_3947::US8629135, SW-06

SMILES: CN(CCCN1c2ccccc2CCc2ccccc12)CC(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=SAPNXPWPAUFAJU-UHFFFAOYSA-N

Data: 27 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 82437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile salt export pump (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.4	30
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Norepinephrine transporter (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent noradrenaline transporter (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1 (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Muscarinic acetylcholine receptor M2 (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M4 (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M5 (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Histamine H1 receptor (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM82437 (CAS_23047-25-8 | NSC_3947 | US8629135, SW-06 | Lof...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair