BDBM8246 3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 6-c

SMILES: c1cc(cc(c1)Cl)C2=C(C(=O)NC2=O)Nc3ccc(c(c3)Cl)O

InChI Key: InChIKey=YYGKSMKAYKZSBC-UHFFFAOYSA-N

Data: 6 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 8246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 alpha (Human)	BDBM8246 (3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Human)	BDBM8246 (3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A1 (Human)	BDBM8246 (3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.21E+3	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 alpha (Human)	BDBM8246 (3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM8246 (3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM8246 (3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain testis-specific protein (Human)	BDBM8246 (3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8246 (3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair