BDBM82507 (+/-)-Methadone::CAS_5967-73-7::METHADONE::Methadone-HCL,(-)::NSC_22266

SMILES: CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=USSIQXCVUWKGNF-UHFFFAOYSA-N

Data: 35 KI  8 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 44 hits for monomerid = 82507   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent translocase ABCB1 (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	512	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type/Kappa-type/Mu-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mas-related G-protein coupled receptor member X2 (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.40E+4	n/a	n/a	7.4	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.945	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		14.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		19.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldehyde oxidase 1 (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Pig)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		37.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		324	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		371	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		405	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		435	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Norepinephrine transporter (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		702	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		728	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		992	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Norepinephrine transporter (Rat)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Bovine)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2B6 (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.62E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM82507 (CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair