BDBM8285 3-(4-chlorophenyl)-4-[methyl(phenyl)amino]-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 7d

SMILES CN(C1=C(C(=O)NC1=O)c1ccc(Cl)cc1)c1ccccc1

InChI Key InChIKey=OXDDQEIQYYBUAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8285   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM8285(3-(4-chlorophenyl)-4-[methyl(phenyl)amino]-2,5-dih...)
Affinity DataIC50:  2.29E+3nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8285(3-(4-chlorophenyl)-4-[methyl(phenyl)amino]-2,5-dih...)
Affinity DataIC50:  2.29E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed