BDBM8290 3-(2,3-dihydro-1H-indol-1-yl)-4-(3-nitrophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 8e

SMILES O=C1NC(=O)C(=C1N1CCc2ccccc12)c1cccc(c1)N(=O)=O

InChI Key InChIKey=BDNALELXSRUQLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8290   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8290(3-(2,3-dihydro-1H-indol-1-yl)-4-(3-nitrophenyl)-2,...)
Affinity DataIC50:  161nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed