BDBM8296 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::CHEMBL102714::SB-216763::cid_176158

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2ccc(Cl)cc2Cl)c2ccccc12

InChI Key: InChIKey=JCSGFHVFHSKIJH-UHFFFAOYSA-N

Data: 3 KI  31 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 37 hits for monomerid = 8296   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-1 (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	269	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3 (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
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POsterior Segregation (Caenorhabditis elegans)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a
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Orotidine 5'-phosphate decarboxylase (Aspergillus niger)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.96E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM8296 (CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		9.10	-10.9	34.3	n/a	n/a	n/a	n/a	7.0	22
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					More data for this Ligand-Target Pair