BDBM8384 CHEMBL260929::N-[6-(1H-pyrrol-2-yl)-1H-indazol-3-yl]cyclopropanecarboxamide::indazole analogue 26
SMILES O=C(Nc1n[nH]c2cc(ccc12)-c1ccc[nH]1)C1CC1
InChI Key InChIKey=YFAZVYJDWIMMBA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 8384
Affinity DataIC50: 320nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataIC50: 497nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 497nMAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair