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BDBM84192 MLS001160615::SMR000709152::[2-(3,4-dimethoxyphenyl)-4-quinolinyl]-(3,5-dimethyl-1-piperidinyl)methanone::[2-(3,4-dimethoxyphenyl)-4-quinolyl]-(3,5-dimethylpiperidino)methanone::[2-(3,4-dimethoxyphenyl)quinolin-4-yl]-(3,5-dimethylpiperidin-1-yl)methanone::cid_3299911

SMILES: COc1ccc(cc1OC)-c1cc(C(=O)N2CC(C)CC(C)C2)c2ccccc2n1

InChI Key: InChIKey=JINFMNIJBGLYFR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 84192   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv7.2


(Rattus norvegicus)
BDBM84192
PNG
(MLS001160615 | SMR000709152 | [2-(3,4-dimethoxyphe...)
Show SMILES COc1ccc(cc1OC)-c1cc(C(=O)N2CC(C)CC(C)C2)c2ccccc2n1
Show InChI InChI=1S/C25H28N2O3/c1-16-11-17(2)15-27(14-16)25(28)20-13-22(26-21-8-6-5-7-19(20)21)18-9-10-23(29-3)24(12-18)30-4/h5-10,12-13,16-17H,11,14-15H2,1-4H3
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PC sid
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Similars

PCBioAssay
n/an/a 1.51E+3n/an/an/an/an/an/a



Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC_KCNQ2_Inh_HFCP_IWS_CRC) Center Affiliation: Johns Hopkins University, School of M...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2W37TT2
More data for this
Ligand-Target Pair