BindingDB logo
myBDB logout

BDBM8474 (2R)-2-[(2-fluorobenzene)sulfonamido]-N-hydroxy-3-methylbutanamide::hydroxamate analogue 11

SMILES: CC(C)[C@@H](NS(=O)(=O)c1ccccc1F)C(=O)NO

InChI Key: InChIKey=KHIJFBYFZGRQIN-UEQNJFAPNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8474   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Anthrax Lethal Factor (LF)


(Bacillus anthracis)
BDBM8474
PNG
((2R)-2-[(2-fluorobenzene)sulfonamido]-N-hydroxy-3-...)
Show SMILES CC(C)[C@@H](NS(=O)(=O)c1ccccc1F)C(=O)NO
Show InChI InChI=1/C11H15FN2O4S/c1-7(2)10(11(15)13-16)14-19(17,18)9-6-4-3-5-8(9)12/h3-7,10,14,16H,1-2H3,(H,13,15)/t10-/s2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.60E+3n/an/an/an/a7.022



Merck Research Laboratories



Assay Description
The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...


Bioorg Med Chem Lett 16: 964-8 (2006)


Article DOI: 10.1016/j.bmcl.2005.10.088
BindingDB Entry DOI: 10.7270/Q2K35RV4
More data for this
Ligand-Target Pair