BindingDB logo
myBDB logout

BDBM84750 (3) 1H-1,2,4-triazol-3-yl-anilines

SMILES: FC(F)(F)c1cccc(c1)-n1cnc(n1)-c1ccccc1Nc1ccncc1

InChI Key: InChIKey=WSKMMKRZESEPDS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 84750   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 1


(Homo sapiens (Human))
BDBM84750
PNG
((3) 1H-1,2,4-triazol-3-yl-anilines)
Show SMILES FC(F)(F)c1cccc(c1)-n1cnc(n1)-c1ccccc1Nc1ccncc1
Show InChI InChI=1S/C20H14F3N5/c21-20(22,23)14-4-3-5-16(12-14)28-13-25-19(27-28)17-6-1-2-7-18(17)26-15-8-10-24-11-9-15/h1-13H,(H,24,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 110n/an/an/an/a7.525



ChemDiv Inc.



Assay Description
In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...


Chem Biol Drug Des 69: 331-7 (2007)


Article DOI: 10.1111/j.1747-0285.2007.00507.x
BindingDB Entry DOI: 10.7270/Q2DR2T12
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM84750
PNG
((3) 1H-1,2,4-triazol-3-yl-anilines)
Show SMILES FC(F)(F)c1cccc(c1)-n1cnc(n1)-c1ccccc1Nc1ccncc1
Show InChI InChI=1S/C20H14F3N5/c21-20(22,23)14-4-3-5-16(12-14)28-13-25-19(27-28)17-6-1-2-7-18(17)26-15-8-10-24-11-9-15/h1-13H,(H,24,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 62n/an/an/an/a7.525



ChemDiv Inc.



Assay Description
In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...


Chem Biol Drug Des 69: 331-7 (2007)


Article DOI: 10.1111/j.1747-0285.2007.00507.x
BindingDB Entry DOI: 10.7270/Q2DR2T12
More data for this
Ligand-Target Pair