BDBM85030 Cetirizine (-) isomer

SMILES c1ccc(cc1)[C@H](c2ccc(cc2)Cl)N3CCN(CC3)CCOCC(=O)O

InChI Key InChIKey=ZKLPARSLTMPFCP-UHFFFAOYSA-N

Data  1 KI  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 85030   

TargetHistamine H1 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85030BDBM85030(Cetirizine (-) isomer)
Affinity DataKd:  0.0110nMAssay Description:Displacement of [3H]-mepyramine from human histamine H1 receptor expressed in HEK293T cells assessed as dissociation rate constant (Koff) incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistamine H1 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85030BDBM85030(Cetirizine (-) isomer)
Affinity DataKi:  100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed