BDBM85447 Epoxy analogue, I(a)
SMILES: N[C@@H](C[C@H]1CO1)C(O)=O
InChI Key: InChIKey=HKPCHCJYQVJLIZ-IMJSIDKUSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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S-Adenosylmethionine Synthase (AdoMet) (Rattus norvegicus) | BDBM85447![]() (Epoxy analogue, I(a)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | 7.00E+3 | -7.31 | 5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |