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BDBM85448 Epoxy analogue, I(b)

InChI string: InChI=1S/C6H11NO3/c1-3-5(10-3)2-4(7)6(8)9/h3-5H,2,7H2,1H3,(H,8,9)/t3-,4+,5+/m1/s1

SMILES: C[C@H]1O[C@H]1C[C@H](N)C(O)=O

InChI Key: InChIKey=QFOIPOGZSOITTR-WISUUJSJSA-N

Data: 1 KI  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 85448   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
S-Adenosylmethionine Synthase (AdoMet)


(Rattus norvegicus)
BDBM85448
PNG
(Epoxy analogue, I(b))
Show SMILES C[C@H]1O[C@H]1C[C@H](N)C(O)=O
Show InChI InChI=1S/C6H11NO3/c1-3-5(10-3)2-4(7)6(8)9/h3-5H,2,7H2,1H3,(H,8,9)/t3-,4+,5+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
6.10E+4 -5.98 1.00E+5n/an/an/an/a7.537



Laboratoire de chimie bioorganique



Assay Description
AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...


J Enzym Inhib 13: 361-7 (1998)

More data for this
Ligand-Target Pair