BDBM8552 2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl)-1,3,4-oxadiazole::oxadiazole-pyridyl containing compound 12

SMILES Ic1cccc(CSc2nnc(o2)-c2ccncc2)c1

InChI Key InChIKey=ZRHRPGSSSVYBRG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 8552   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Novo Nordisk

LigandPNGBDBM8552(2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50:  390nMpH: 7.0 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Novo Nordisk

LigandPNGBDBM8552(2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Novo Nordisk

LigandPNGBDBM8552(2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50:  390nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Novo Nordisk

LigandPNGBDBM8552(2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50:  390nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM8552(2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM8552(2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed