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BDBM86076 Tetraketone, 10

SMILES: CCOc1ccc(cc1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O

InChI Key: InChIKey=CALUMVNDYOMHDD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 86076   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lipoxygenase


(Homo sapiens)
BDBM86076
PNG
(Tetraketone, 10)
Show SMILES CCOc1ccc(cc1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O
Show InChI InChI=1S/C25H32O5/c1-6-30-16-9-7-15(8-10-16)21(22-17(26)11-24(2,3)12-18(22)27)23-19(28)13-25(4,5)14-20(23)29/h7-10,21-23H,6,11-14H2,1-5H3
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Similars

Article
PubMed
n/an/a 3.08E+4n/an/an/an/a8.025



Pharmaceutical Research Centre



Assay Description
In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...


J Enzyme Inhib Med Chem 23: 62-9 (2008)


Article DOI: 10.1080/14756360701408754
BindingDB Entry DOI: 10.7270/Q2P849FN
More data for this
Ligand-Target Pair