BDBM8611 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonitrile::CHEMBL468419::CHEMBL9298::Fadrozole::US9271963, Fadrozole

SMILES: N#Cc1ccc(cc1)C1CCCc2cncn12

InChI Key: InChIKey=CLPFFLWZZBQMAO-UHFFFAOYSA-N

Data: 5 KI  83 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 90 hits for monomerid = 8611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rat)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rat)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.00400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Mouse)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	7.4	32
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28.3	n/a	n/a	n/a	n/a	7.4	32
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29.5	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM8611 (CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
					More data for this Ligand-Target Pair