BDBM86239 CAS_3046161::MDA,R(-)::NSC_3046161

SMILES C[C@@H](N)Cc1ccc2OCOc2c1

InChI Key InChIKey=NGBBVGZWCFBOGO-SSDOTTSWSA-N

Data  7 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 86239   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Affinity DataKi:  197nMAssay Description:Antagonist activity against human progesterone receptor (hPR) in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNorepinephrine transporter(RAT)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Affinity DataKi:  290nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Affinity DataKi:  310nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Affinity DataKi:  900nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Affinity DataKi:  3.42E+3nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Affinity DataKi:  1.30E+4nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Affinity DataEC50:  900nMAssay Description:Activity at DAT in rat synaptosomes assessed as release of [3H]DA after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Affinity DataEC50:  310nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Affinity DataEC50:  1.17E+4nMAssay Description:Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Macaca mulatta)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)
Affinity DataEC50:  2.48E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed