BindingDB PrimarySearch

BDBM22165 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine::CHEMBL153260::CHEMBL281594::CHEMBL542933::CHEMBL543876::GBR 12909::GBR-12909::NCGC00015300::US9944618, Compound ID No. 175::Vanoxerine

SMILES: c1ccc(cc1)CCCN2CCN(CC2)CCOC(c3ccc(cc3)F)c4ccc(cc4)F

InChI Key: InChIKey=NAUWTFJOPJWYOT-UHFFFAOYSA-N

Data: 106 KI 92 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 198 hits for monomerid = 22165
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
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Arachidonate 15-lipoxygenase (Pseudomonas aeruginosa)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	25
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Sodium-dependent noradrenaline transporter (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent serotonin transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent serotonin transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent serotonin transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	86.6	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	19.3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	741	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent noradrenaline transporter (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Human)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	21.1	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	14.2	n/a	n/a	n/a	n/a	n/a	n/a
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Transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent serotonin transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
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Transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	496	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM22165 (Vanoxerine \| CHEMBL542933 \| GBR-12909 \| CHEMBL5438...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
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