BDBM86731 CAS_74191-85-8::Doxazosin::UK 33,274

SMILES: COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1COc2ccccc2O1

InChI Key: InChIKey=RUZYUOTYCVRMRZ-UHFFFAOYSA-N

Data: 21 KI  6 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 86731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	589	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
HLA class I histocompatibility antigen, A alpha chain (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rat)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		0.324	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		0.537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		0.537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		0.631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		0.776	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		0.813	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		0.813	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		0.813	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		0.813	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Mouse)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		729	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Human)	BDBM86731 (UK 33,274 | CAS_74191-85-8 | Doxazosin) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair