BDBM13530 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide::CHEMBL941::Gleevec::Imatinib::Imatinib, 21::N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide::STI-571::STI571::US10906896, Cpd imatinib::US11649218, Example Imatinib::US11725005, Compound imatinib::US20250129067, Compound Imatinib::US9255107, Imatinib::cid_5291::med.21724, Compound 6

SMILES: CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1

InChI Key: InChIKey=KTUFNOKKBVMGRW-UHFFFAOYSA-N

Data: 62 KI  235 IC50  842 Kd  9 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1147 hits for monomerid = 13530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 [201-500] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [201-500,Q252H] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	20	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [201-500,Y253F] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	40	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [201-500,E255K] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	100	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [201-500,M351T] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	10	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [201-500,F359V] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	20	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [201-500,H396P] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [201-500,T315I] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [201-500,T315N] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [N822K] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V559D] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V559D,T670I] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 19 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 [R432A] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	7.4	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK4 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	7.4	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	19	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.700	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 [A642S] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	15	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase FRK (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Blk (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fgr (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lyn (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TNNI3K (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 20 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [1-999,Q252H] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL2 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ephrin type-A receptor 8 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-G-associated kinase (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK4 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	372	n/a	70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [1-999,Q252H] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [1-999,Q252H] (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Putative glycogen synthase kinase 3 alpha (Corn smut fungus)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Aurora kinase A (Human)	BDBM13530 (cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair