BDBM86751 CHEMBL14935::LY 293558::LY-293558
SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](CCc3nnn[nH]3)CC[C@H]2CN1
InChI Key InChIKey=ZXFRFPSZAKNPQQ-YTWAJWBKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 86751
Affinity DataKi: 2.21E+3nMAssay Description:Inhibition of [3H]-AMPA binding to human Ionontropic glutamate receptor 2More data for this Ligand-Target Pair
Affinity DataKi: 3.20E+3nMAssay Description:Binding affinity to GluR2More data for this Ligand-Target Pair
Affinity DataKi: 3.20E+3nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2More data for this Ligand-Target Pair
Affinity DataKi: 4.16E+3nMAssay Description:Inhibition of [3H]-KA binding to iontropic glutamate receptor 5More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 4.20E+3nMAssay Description:Binding affinity to GluR5More data for this Ligand-Target Pair
Affinity DataKi: 9.20E+3nMAssay Description:Binding affinity to GluR1More data for this Ligand-Target Pair
Affinity DataKi: 9.20E+3nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 1More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 3.20E+4nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 3More data for this Ligand-Target Pair
Affinity DataKi: 3.20E+4nMAssay Description:Binding affinity to GluR3More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 4More data for this Ligand-Target Pair
Affinity DataKi: 5.05E+4nMAssay Description:Binding affinity to GluR4More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: >1.00E+5nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human AMPA receptor Ionotropic glutamate receptor ionotropic kainate 2More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: >1.00E+5nMAssay Description:Ability to displace binding of [3H]KA to recombinant human KA receptor Ionotropic glutamate receptor ionotropic kainate 2 expressed in EK 293 cell me...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to GluR7More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to GluR6More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of [3H]-KA binding to iontropic glutamate receptor 6More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of GluK1 receptor (unknown origin)More data for this Ligand-Target Pair