BDBM86850 1-(2,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041628::NSC_16041628

SMILES CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1ccc(F)cc1F

InChI Key InChIKey=NIQWPNGICRVKCM-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 86850   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by PDSP Ki Database
LigandPNGBDBM86850(1-(2,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  0.690nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by PDSP Ki Database
LigandPNGBDBM86850(1-(2,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  2.70nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by PDSP Ki Database
LigandPNGBDBM86850(1-(2,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by PDSP Ki Database
LigandPNGBDBM86850(1-(2,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  26.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by PDSP Ki Database
LigandPNGBDBM86850(1-(2,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  35.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by PDSP Ki Database
LigandPNGBDBM86850(1-(2,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  76nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by PDSP Ki Database
LigandPNGBDBM86850(1-(2,4-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  475nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed