BDBM87054 Bisanilinopyrimidine inhibitor, 8::Bisanilinopyrimidine, 6i::US9249124, 32

SMILES: c1ccc(c(c1)Nc2ccnc(n2)Nc3ccc(cc3)C(=O)O)Br

InChI Key: InChIKey=NCXZWZMYZVWHNN-UHFFFAOYSA-N

Data: 5 IC50  2 Kd  1 ITC

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 87054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Human)	BDBM87054 (Bisanilinopyrimidine, 6i | Bisanilinopyrimidine in...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	13	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM87054 (Bisanilinopyrimidine, 6i | Bisanilinopyrimidine in...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM87054 (Bisanilinopyrimidine, 6i | Bisanilinopyrimidine in...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM87054 (Bisanilinopyrimidine, 6i | Bisanilinopyrimidine in...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.4	18
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM87054 (Bisanilinopyrimidine, 6i | Bisanilinopyrimidine in...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	13	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair