BDBM8733 (2E)-N-methyl-N-[(1-methyl-1H-indol-3-yl)methyl]-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)prop-2-enamide::(E)-N-Methyl-N-(1-methyl-1H-indol-3-ylmethyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide::indole naphthyridinone 29

SMILES: Cn1cc(c2c1cccc2)CN(C)C(=O)\C=C\c3cc4c(nc3)NC(=O)CC4

InChI Key: InChIKey=VAZMNDXVXVUKFY-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8733   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM8733 ((2E)-N-methyl-N-[(1-methyl-1H-indol-3-yl)methyl]-3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	6.5	30
TBA									Citation and Details
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Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Escherichia coli (strain K12))	BDBM8733 ((2E)-N-methyl-N-[(1-methyl-1H-indol-3-yl)methyl]-3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	6.5	30
TBA									Citation and Details
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Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Haemophilus influenzae (strain ATCC 51907 / DSM 11...)	BDBM8733 ((2E)-N-methyl-N-[(1-methyl-1H-indol-3-yl)methyl]-3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	30
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Trans-2-enoyl-ACP reductase II (Streptococcus pneumoniae)	BDBM8733 ((2E)-N-methyl-N-[(1-methyl-1H-indol-3-yl)methyl]-3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair