BDBM8735 (2E)-N-[(1,2-dimethyl-1H-indol-3-yl)methyl]-N-methyl-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)prop-2-enamide::(E)-N-(1,2-Dimethyl-1H-indol-3-ylmethyl)-N-methyl-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide::indole naphthyridinone 31

SMILES: Cc1c(c2ccccc2n1C)CN(C)C(=O)/C=C/c3cc4c(nc3)NC(=O)CC4

InChI Key: InChIKey=PVNPCRMKZHRPEV-UHFFFAOYSA-N

Data: 6 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 8735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM8735 ((E)-N-(1,2-Dimethyl-1H-indol-3-ylmethyl)-N-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	6.5	30
TBA									Citation and Details
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Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Escherichia coli (strain K12))	BDBM8735 ((E)-N-(1,2-Dimethyl-1H-indol-3-ylmethyl)-N-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	6.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Haemophilus influenzae (strain ATCC 51907 / DSM 11...)	BDBM8735 ((E)-N-(1,2-Dimethyl-1H-indol-3-ylmethyl)-N-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
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Trans-2-enoyl-ACP reductase II (Streptococcus pneumoniae)	BDBM8735 ((E)-N-(1,2-Dimethyl-1H-indol-3-ylmethyl)-N-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM8735 ((E)-N-(1,2-Dimethyl-1H-indol-3-ylmethyl)-N-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Haemophilus influenzae (strain ATCC 51907 / DSM 11...)	BDBM8735 ((E)-N-(1,2-Dimethyl-1H-indol-3-ylmethyl)-N-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair