BDBM87351 Amsacrine hydrochloride::CHEMBL43::MLS002153376::N-[4-(9-acridinylamino)-3-methoxyphenyl]methanesulfonamide;hydrochloride::N-[4-(acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide;hydrochloride::N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide::N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide;hydrochloride::SMR000875352::cid_148673::m-AMSA

SMILES: COc1cc(ccc1Nc2c3ccccc3nc4c2cccc4)NS(=O)(=O)C

InChI Key: InChIKey=XCPGHVQEEXUHNC-UHFFFAOYSA-N

Data: 2 KI  21 IC50  8 EC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 87351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tegument protein VP16 (HHV-1)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA topoisomerase 2-alpha/2-beta (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 1 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA topoisomerase 2-beta (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
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Aldehyde oxidase 1 (Rat)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aldehyde oxidase (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde oxidase 1 (Rat)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific histone demethylase 1A (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-beta (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor coactivator 1 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor coactivator 3 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>443	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aldehyde oxidase 1 (Rabbit)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM87351 (m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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