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BDBM87764 US10245267, Example 799::US10709712, Example 799::US9694016, 799

SMILES: Cc1ncc(NC(=O)c2ccnc(c2)C(C)(F)F)cc1-c1cc(N2CCOCC2)n2nccc2n1

InChI Key: InChIKey=MUGSHVQXVRLFFT-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 87764   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase B-raf [V600E]


(Human)
BDBM87764
PNG
(US9694016, 799 | US10245267, Example 799 | US10709...)
GoogleScholar
UniChem
n/an/a 1.5n/an/an/an/a7.525


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340E,Y341E]


(Human)
BDBM87764
PNG
(US9694016, 799 | US10245267, Example 799 | US10709...)
GoogleScholar
UniChem
n/an/a 0.400n/an/an/an/a7.525


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E]


(Human)
BDBM87764
PNG
(US9694016, 799 | US10245267, Example 799 | US10709...)
GoogleScholar
UniChem
n/an/a 1.5n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM87764
PNG
(US9694016, 799 | US10245267, Example 799 | US10709...)
GoogleScholar
UniChem
n/an/a 0.400n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E]


(Human)
BDBM87764
PNG
(US9694016, 799 | US10245267, Example 799 | US10709...)
GoogleScholar
UniChem
n/an/a 1.5n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM87764
PNG
(US9694016, 799 | US10245267, Example 799 | US10709...)
GoogleScholar
UniChem
n/an/a 0.400n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair