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BDBM88120 US10245267, Example 1156::US10709712, Example 1156::US9694016, 1156

SMILES: Cc1ccc(NC(=O)c2ccnc(c2)C(F)(F)F)cc1-c1cc(OCCO)nc(c1)N1CCOCC1

InChI Key: InChIKey=UEPXBTCUIIGYCY-UHFFFAOYSA-N

Data: 13 IC50  5 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 88120   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/an/a 14n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase A-Raf


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 414n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 49n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 3.70n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 4n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 3.70n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 1n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 8.60n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 8.60n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 78n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/an/a 1.30n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/an/a 3.60n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a>1.00E+4n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E]


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 0.730n/an/an/an/a7.525


TBA



Citation and Details
More data for this
Ligand-Target Pair
Discoidin domain-containing receptor 2


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/an/a 10n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/an/a 1.80n/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 0.400n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 0.200n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/an/an/a 14n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase A-Raf


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a>10n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 0.200n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E]


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 0.730n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 0.200n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E]


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 0.730n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340E,Y341E]


(Human)
BDBM88120
PNG
(US9694016, 1156 | US10245267, Example 1156 | US107...)
GoogleScholar
UniChem
n/an/a 0.200n/an/an/an/a7.525


TBA



Citation and Details
More data for this
Ligand-Target Pair