BDBM8826 3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea::Biochemistry 469551 Compound 3::CHEMBL196363::KDR Kinase Inhibitor, 1::N-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 76

SMILES: Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3ncnc(N)c23)c1

InChI Key: InChIKey=DZSUJUOJJJCWGG-UHFFFAOYSA-N

Data: 4 KI  15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 8826   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.02	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	724	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.03	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Aromatase (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK2 (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		64	-9.71	n/a	n/a	n/a	n/a	n/a	7.5	22
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Serine/threonine-protein kinase PLK4 (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK3 (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM8826 (CHEMBL196363 | 3-(4-{4-aminothieno[2,3-d]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+4	>-6.34	n/a	n/a	n/a	n/a	n/a	7.5	22
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