BDBM88305 US9695118, 137

SMILES: CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1ccc(CN2CCCC[C@H]2CNC)c(c1)C(F)(F)F

InChI Key: InChIKey=ACCKFOUYMYBULX-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 88305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human))	BDBM88305 (US9695118, 137) Show SMILES CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1ccc(CN2CCCC[C@H]2CNC)c(c1)C(F)(F)F Show InChI InChI=1S/C25H31ClF3N3O3S/c1-3-36(34,35)23-10-9-20(26)12-19(23)14-31-24(33)17-7-8-18(22(13-17)25(27,28)29)16-32-11-5-4-6-21(32)15-30-2/h7-10,12-13,21,30H,3-6,11,14-16H2,1-2H3,(H,31,33)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	25
Chugai Seiyaku Kabushiki Kaisha US Patent					Assay Description DDR1 binding activity was measured by the LanthaScreen (Registered trademark) Eu Kinase Binding Assay (manufactured by Life Technologies Corporation)...				US Patent US9695118 (2017) BindingDB Entry DOI: 10.7270/Q2736P1T
					More data for this Ligand-Target Pair