BDBM8858 3-{4-[4-amino-6-(2-hydroxyethyl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-1-(3-methylphenyl)urea::CHEMBL197353::N-{4-[4-Amino-6-(2-hydroxyethyl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 84

SMILES: Cc1cccc(NC(=O)Nc2ccc(cc2)-c2c(CCO)sc3ncnc(N)c23)c1

InChI Key: InChIKey=XLDWKHLQBFECEA-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 8858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM8858 (CHEMBL197353 | 3-{4-[4-amino-6-(2-hydroxyethyl)thi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM8858 (CHEMBL197353 | 3-{4-[4-amino-6-(2-hydroxyethyl)thi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM8858 (CHEMBL197353 | 3-{4-[4-amino-6-(2-hydroxyethyl)thi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM8858 (CHEMBL197353 | 3-{4-[4-amino-6-(2-hydroxyethyl)thi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM8858 (CHEMBL197353 | 3-{4-[4-amino-6-(2-hydroxyethyl)thi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	257	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM8858 (CHEMBL197353 | 3-{4-[4-amino-6-(2-hydroxyethyl)thi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM8858 (CHEMBL197353 | 3-{4-[4-amino-6-(2-hydroxyethyl)thi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	37.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair