BDBM8860 3-{4-[4-amino-6-(3-hydroxypropyl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-1-(3-methylphenyl)urea::CHEMBL198297::KDR Kinase Inhibitor, 4::N-{4-[4-Amino-6-(3-hydroxypropyl)thieno[2,3-d]pyrimid-5-yl]phenyl}-N1-(3-methylphenyl)urea::Thienopyrimidine deriv. 86

SMILES: Cc1cccc(NC(=O)Nc2ccc(cc2)-c2c(CCCO)sc3ncnc(N)c23)c1

InChI Key: InChIKey=QFPRMYTURWHCEE-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 8860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM8860 (CHEMBL198297 | N-{4-[4-Amino-6-(3-hydroxypropyl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM8860 (CHEMBL198297 | N-{4-[4-Amino-6-(3-hydroxypropyl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM8860 (CHEMBL198297 | N-{4-[4-Amino-6-(3-hydroxypropyl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM8860 (CHEMBL198297 | N-{4-[4-Amino-6-(3-hydroxypropyl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM8860 (CHEMBL198297 | N-{4-[4-Amino-6-(3-hydroxypropyl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM8860 (CHEMBL198297 | N-{4-[4-Amino-6-(3-hydroxypropyl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM8860 (CHEMBL198297 | N-{4-[4-Amino-6-(3-hydroxypropyl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM8860 (CHEMBL198297 | N-{4-[4-Amino-6-(3-hydroxypropyl)th...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair