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BDBM88930 (E)-3-(2-Methyl-1H-indol-3-yl)-1-pyridin-4-yl-propenone::(E)-3-(2-methyl-1H-indol-3-yl)-1-(4-pyridyl)prop-2-en-1-one::(E)-3-(2-methyl-1H-indol-3-yl)-1-pyridin-4-yl-2-propen-1-one::(E)-3-(2-methyl-1H-indol-3-yl)-1-pyridin-4-yl-prop-2-en-1-one::(E)-3-(2-methyl-1H-indol-3-yl)-1-pyridin-4-ylprop-2-en-1-one::MLS001049159::SMR000427793::cid_5718958

SMILES: Cc1[nH]c2ccccc2c1\C=C\C(=O)c1ccncc1

InChI Key: InChIKey=LKXOPRJGYYWDEI-VOTSOKGWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 88930   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
26S Proteasome regulatory subunit Rpn11 (Rpn11)


(Homo sapiens (Human))
BDBM88930
PNG
((E)-3-(2-Methyl-1H-indol-3-yl)-1-pyridin-4-yl-prop...)
Show SMILES Cc1[nH]c2ccccc2c1\C=C\C(=O)c1ccncc1
Show InChI InChI=1S/C17H14N2O/c1-12-14(15-4-2-3-5-16(15)19-12)6-7-17(20)13-8-10-18-11-9-13/h2-11,19H,1H3/b7-6+
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
Purchase

PC cid
PC sid
UniChem
PCBioAssay
n/an/a 3.88E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2PC30Z9
More data for this
Ligand-Target Pair
Thrombin


(Bos taurus (Bovine))
BDBM88930
PNG
((E)-3-(2-Methyl-1H-indol-3-yl)-1-pyridin-4-yl-prop...)
Show SMILES Cc1[nH]c2ccccc2c1\C=C\C(=O)c1ccncc1
Show InChI InChI=1S/C17H14N2O/c1-12-14(15-4-2-3-5-16(15)19-12)6-7-17(20)13-8-10-18-11-9-13/h2-11,19H,1H3/b7-6+
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

PC cid
PC sid
UniChem
PCBioAssay
n/an/a 4.84E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2JM286J
More data for this
Ligand-Target Pair