BDBM8898 1-(3,4-Dihydronaphthalen-2-yl)-1H-imidazole::Dihydronaphthalene 13::US9271963, 45

SMILES C1Cc2ccccc2C=C1n1ccnc1

InChI Key InChIKey=DHUCLDOIXQGVDQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8898   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8898(1-(3,4-Dihydronaphthalen-2-yl)-1H-imidazole | Dihy...)
Affinity DataIC50:  639nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8898(1-(3,4-Dihydronaphthalen-2-yl)-1H-imidazole | Dihy...)
Affinity DataIC50:  638nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8898(1-(3,4-Dihydronaphthalen-2-yl)-1H-imidazole | Dihy...)
Affinity DataIC50:  334nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed