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BDBM89303 MLS000702080::SMR000226912::[3-azanylidene-4-(benzimidazol-2-ylidene)-2-phenyl-1H-pyridazin-6-yl]-(furan-2-yl)methanone::[4-(2-benzimidazolylidene)-3-imino-2-phenyl-1H-pyridazin-6-yl]-(2-furanyl)methanone::[4-(benzimidazol-2-ylidene)-3-imino-2-phenyl-1H-pyridazin-6-yl]-(2-furyl)methanone::[4-(benzimidazol-2-ylidene)-3-imino-2-phenyl-1H-pyridazin-6-yl]-(furan-2-yl)methanone::[5-(1H-benzimidazol-2-yl)-6-imino-1-phenyl-1,6-dihydro-3-pyridazinyl](2-furyl)methanone::cid_5453593

SMILES: N=c1c(cc(nn1-c1ccccc1)C(=O)c1ccco1)-c1nc2ccccc2[nH]1

InChI Key: InChIKey=SHZKHMMWAQIQNH-UHFFFAOYSA-N

Data: 2 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 89303   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Wnt-3a


(Mus musculus)
BDBM89303
PNG
(MLS000702080 | SMR000226912 | [3-azanylidene-4-(be...)
Show SMILES N=c1c(cc(nn1-c1ccccc1)C(=O)c1ccco1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C22H15N5O2/c23-21-15(22-24-16-9-4-5-10-17(16)25-22)13-18(20(28)19-11-6-12-29-19)26-27(21)14-7-2-1-3-8-14/h1-13,23H,(H,24,25)
PDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 1.68E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q25B012X
More data for this
Ligand-Target Pair
Zinc finger protein GLI1


(Mus musculus)
BDBM89303
PNG
(MLS000702080 | SMR000226912 | [3-azanylidene-4-(be...)
Show SMILES N=c1c(cc(nn1-c1ccccc1)C(=O)c1ccco1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C22H15N5O2/c23-21-15(22-24-16-9-4-5-10-17(16)25-22)13-18(20(28)19-11-6-12-29-19)26-27(21)14-7-2-1-3-8-14/h1-13,23H,(H,24,25)
PDB
MMDB

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a>2.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.1930
BindingDB Entry DOI: 10.7270/Q2862F26
More data for this
Ligand-Target Pair