BDBM8971 CHEMBL129108::N-[8-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)octyl]-1,2,3,4-tetrahydroacridin-9-amine::Tacrine Dimer 4g

SMILES: c1ccc2c(c1)c(c3c(n2)CCCC3)NCCCCCCCCSc4c5ccccc5nc6c4CCCC6

InChI Key: InChIKey=COEYCPFFRLYNSC-UHFFFAOYSA-N

Data: 10 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 8971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxylic ester hydrolase (Horse)	BDBM8971 (CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cholinesterase (Human)	BDBM8971 (CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8971 (CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...) Show SMILES Show InChI	GoogleScholar	UniChem		1.65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8971 (CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...) Show SMILES Show InChI	GoogleScholar	UniChem		1.65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8971 (CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8971 (CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...) Show SMILES Show InChI	GoogleScholar	UniChem		27.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8971 (CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...) Show SMILES Show InChI	GoogleScholar	UniChem		27.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8971 (CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...) Show SMILES Show InChI	GoogleScholar	UniChem		28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8971 (CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...) Show SMILES Show InChI	GoogleScholar	UniChem		250	-9.00	n/a	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM8971 (CHEMBL129108 | N-[8-(1,2,3,4-tetrahydroacridin-9-y...) Show SMILES Show InChI	GoogleScholar	UniChem		250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair