BDBM90222 (2Z)-2-[4-(4-fluorophenyl)-3-methyl-1,3-thiazol-2-ylidene]-2-(5-morpholin-4-yl-4-phenyl-1,2,4-triazol-3-yl)acetonitrile;hydrobromide::(2Z)-2-[4-(4-fluorophenyl)-3-methyl-1,3-thiazol-2-ylidene]-2-(5-morpholin-4-yl-4-phenyl-1,2,4-triazol-3-yl)ethanenitrile;hydrobromide::(2Z)-2-[4-(4-fluorophenyl)-3-methyl-2-thiazolylidene]-2-[5-(4-morpholinyl)-4-phenyl-1,2,4-triazol-3-yl]acetonitrile;hydrobromide::(2Z)-2-[4-(4-fluorophenyl)-3-methyl-4-thiazolin-2-ylidene]-2-(5-morpholino-4-phenyl-1,2,4-triazol-3-yl)acetonitrile;hydrobromide::MLS000391956::SMR000260989::cid_15944949

SMILES: CN1\C(SC=C1c1ccc(F)cc1)=C(/C#N)c1nnc(N2CCOCC2)n1-c1ccccc1

InChI Key: InChIKey=LMPJHCKNAFPGOT-ATJXCDBQSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 90222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
corticotropin releasing factor-binding protein (Homo sapiens (Human))	BDBM90222 ((2Z)-2-[4-(4-fluorophenyl)-3-methyl-1,3-thiazol-2-...) Show SMILES CN1\C(SC=C1c1ccc(F)cc1)=C(/C#N)c1nnc(N2CCOCC2)n1-c1ccccc1 Show InChI InChI=1S/C24H21FN6OS/c1-29-21(17-7-9-18(25)10-8-17)16-33-23(29)20(15-26)22-27-28-24(30-11-13-32-14-12-30)31(22)19-5-3-2-4-6-19/h2-10,16H,11-14H2,1H3/b23-20-	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PCBioAssay	n/a	n/a	n/a	n/a	>5.30E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) Article DOI: 10.1038/nchembio.2085 BindingDB Entry DOI: 10.7270/Q2VX0F3D
					More data for this Ligand-Target Pair