BDBM9036 2-(5-Bromo-1H-indol-3-yl)-N-[7-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]acetamide::2-(5-bromo-1H-indol-3-yl)-N-{7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl}acetamide::Indole-Tacrine Heterodimer 19

SMILES Clc1ccc2c(NCCCCCCCNC(=O)Cc3c[nH]c4ccc(Br)cc34)c3CCCCc3nc2c1

InChI Key InChIKey=FEAVRTOEDVZKCJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9036   

TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9036(2-(5-Bromo-1H-indol-3-yl)-N-[7-(6-chloro-1,2,3,4-t...)
Affinity DataIC50:  0.600nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM9036(2-(5-Bromo-1H-indol-3-yl)-N-[7-(6-chloro-1,2,3,4-t...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9036(2-(5-Bromo-1H-indol-3-yl)-N-[7-(6-chloro-1,2,3,4-t...)
Affinity DataIC50:  1.70nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed