BDBM92336 Dipeptide nitrile, 10
SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC#N)C#N
InChI Key InChIKey=NHZZJQFLKHUHMA-GJZGRUSLSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 92336
Affinity DataKi: >330nMpH: 6.0Assay Description:Inhibition of human liver cathepsin B using Cbz-Arg-Arg-pNA as substrate at pH 6 incubated for 30 mins measured for 20 mins by photometrical analysisMore data for this Ligand-Target Pair
Affinity DataKi: 840nM ΔG°: -8.62kcal/molepH: 6.5 T: 2°CAssay Description:Cathepsin enzyme activities were calculated from kinetic measurements performed by fluorimetric detection of the product 7-amino-4-methylcoumarin at ...More data for this Ligand-Target Pair
Affinity DataKi: 900nM ΔG°: -8.57kcal/molepH: 6.0 T: 2°CAssay Description:Cathepsin enzyme activities were calculated from kinetic measurements performed by fluorimetric detection of the product 7-amino-4-methylcoumarin at ...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nM ΔG°: -8.12kcal/molepH: 6.5 T: 2°CAssay Description:Papain enzyme activities were determined by spectrophotometric detection of the product p-nitroaniline at 25 C in a a multicell holder (parallel meas...More data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nM ΔG°: -7.38kcal/molepH: 5.0 T: 2°CAssay Description:Cathepsin enzyme activities were calculated from kinetic measurements performed by fluorimetric detection of the product 7-amino-4-methylcoumarin at ...More data for this Ligand-Target Pair