BDBM92408 NS3 protease inhibitor, analog 1

SMILES COc1ccc2c(O[C@@H]3CC(N(C3)C(=O)[C@@H](NC(=O)OC3CCCC3)C(C)(C)C)C(=O)N[C@@]3(CC3C=C)C(O)=O)cc(nc2c1)-c1csc(NC(=O)C(C)C)n1

InChI Key InChIKey=GEXHIQCMKLNKQH-WAETZTCYSA-N

Data  1 KI  1 Koff  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 92408   

TargetGenome polyprotein [1027-1206,R1052K](Hepatitis C virus)
Boehringer Ingelheim (Canada)

LigandPNGBDBM92408(NS3 protease inhibitor, analog 1)
Affinity DataKi:  1.89nM Kon:  0.00220M-1s-1 Koff:  1.10E+6s-1pH: 8.0Assay Description:Kinetic analysis of NS3 inhibitor binding experiment were performed using the KinTek stopped flow instrument (SF-2005; excitation, 325 nm; and emissi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed