BDBM92446 Inhibitor, 16

SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)c1ccc(cc1)-c1cc(cs1)-c1ccccc1

InChI Key InChIKey=ADDJDJQFPKUMAF-SFHVURJKSA-N

Data  10 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 92446   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat Á

LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataKi:  2.5nM ΔG°:  -11.7kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Commissariat Á

LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataKi:  127nM ΔG°:  -9.40kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Commissariat Á

LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataKi:  299nM ΔG°:  -8.89kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Commissariat Á

LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataKi:  501nM ΔG°:  -8.59kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Commissariat Á

LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataKi:  671nM ΔG°:  -8.42kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Commissariat Á

LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataKi:  874nM ΔG°:  -8.59kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Commissariat Á

LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataKi:  968nM ΔG°:  -8.20kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Commissariat Á

LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataKi:  1.26E+3nM ΔG°:  -8.04kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Commissariat Á

LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataKi:  2.23E+3nM ΔG°:  -7.70kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Commissariat Á

LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataKi:  5.82E+3nM ΔG°:  -7.14kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat Á

LigandPNGBDBM92446(Inhibitor, 16)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate by spectrophotometric methodMore data for this Ligand-Target Pair