BDBM92596 Sapintoxin D
SMILES CCCC(=O)O[C@@]12C(C3CC(=O)C[C@@]4(O)C(C=C(C)C4=O)[C@]3(O)[C@@H](C)[C@H]1OC(=O)c1ccccc1NC)C2(C)C
InChI Key InChIKey=PUIKISPVMMUIMT-JMXWTWJISA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 92596
Affinity DataKi: 0.140nM ΔG°: -13.1kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 5.90nM ΔG°: -11.0kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase MRCK beta(Homo sapiens (Human))
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 12.6nM ΔG°: -10.5kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Affinity DataKi: 18.2nM ΔG°: -10.3kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair